Richard G. Petty, MD

Jazz and the Brain

It is remarkable how good the brain is at coordinating multiple regions at once. A new study published in today's issue of the journal Public Library of Science (PLoS) One has used functional magnetic resonance scanning (fMRI) to examine musicians engaged in highly creative and spontaneous jazz improvisation. They found that a large region of the brain involved in monitoring one's performance is shut down, while a small region involved in organizing self-initiated thoughts and behaviors is highly activated. The researchers propose that this and several related patterns are likely to be key indicators of a brain that is engaged in highly creative thought.

During the study, six highly trained jazz musicians played keyboard under two conditions. In the first scenario, called the Scale paradigm, the music was based on a simple C major scale. Using only their right hand, the volunteers first played the scale up and down in quarter notes. Next, they were asked to improvise, though they were limited to playing quarter notes within the C major scale.

The second scenario, called the Jazz paradigm, examined higher-level musical improvisation. This paradigm was based on a novel blues melody that the volunteers had memorized beforehand, and had been written by one of the researchers. Again, using only their right hand, the musicians played the tune exactly as they had memorized it, only this time accompanied through headphones by a pre-recorded jazz quartet. When they were asked to improvise, the musicians listened to the same audio background, but they were free to spontaneously play whatever notes they wished.

The brain scans were nearly identical for the low-level and high-level forms of improvisation, supporting the idea that the change in neural activity was due to creativity and not the complexity of the task.

Much of the change between improvisation and memorization occurred in the prefrontal cortex, the region of the frontal lobe of the brain that helps us think and problem-solve. It is also involved in generating the sense of self. The dorsolateral prefrontal cortex is responsible for monitoring our own performance and it shuts down completely during improvisation, while the much smaller, centrally located region at the foremost part of the brain – the medial prefrontal cortex - increases in activity. The medial prefrontal cortex is believed to be involved in self-initiated thoughts and behaviors, and it becomes very active when a person describes an event that has happened to him or makes up a story.

The suppression of inhibitory, self-monitoring brain mechanisms helps to promote the free flow of novel ideas and impulses. This is an unusual pattern of brain activity that closely resembles the pattern seen in people when they are dreaming.

Another unusual finding was that there was increased neural activity in each of the sensory areas during improvisation, including those responsible for touch, hearing and vision, despite the fact that there were no significant differences in what individuals were hearing, touching and seeing during both memorized and improvised conditions. This suggests that when the brain wants to be creative, a whole range of sensorimotor processing is increased. At the same time systems that regulate emotion were also engaged during improvisation.

As someone who has done a lot of brain imaging, and has spent many hours inside scanners, this whole piece of work is dazzling from a technical point of view. The hardy musicians had to lie on their backs with their heads and torsos inside the scanner and their knees bent upward. They had to use a plastic keyboard, which was shortened to fit inside the scanner and which rested on their knees. A mirror placed over the volunteers' eyes, together with the headphones, helped the musicians see and hear what they were playing.

Just thinking about it makes me queasy.

“Words are the children of reason and, therefore, can't explain it. They really can't translate feeling because they're not part of it. That's why it bugs me when people try to analyze jazz as an intellectual theorem. It's not. It's feeling.”
--Bill Evans (American Jazz Pianist, 1929-1980)

“Jazz tickles your muscles, symphonies stretch your soul.”
--Paul Whiteman (American Musician and Bandleader, called the King of Jazz for popularizing a musical style that helped to introduce jazz to mainstream audiences during the 1920s and 1930s, 1890-1967)

“Jazz music is an intensified feeling of nonchalance.”
--Françoise Sagan (French Novelist and Dramatist, 1935-2004)

Schizophrenia and Evolution

Schizophrenia remains one of the cruelest illnesses ever to afflict humanity. There are more theories about it than any other problem, and we may be getting closer to understanding why it seems to occur only in humans, and at roughly the same rate throughout the world. One idea is that the genetic predisposition to schizophrenia might have evolved as a secondary consequence of selection for human cognitive traits. As humans have evolved so has the brain, and it has become more lateralized, so this might explain the association between schizophrenia and handedness.

Several genes with strong associations to schizophrenia have evolved rapidly during human evolution, according to new research in the Proceedings of the Royal Society B this week.

In support of the cognition/schizophrenia hypothesis, researchers Dr Steve Dorus from the University of Bath, who worked with Dr Bernard Crespi from Simon Fraser University in Canada and Dr Kyle Summers from East Carolina University in the United States found that these genes had been positively selected.

They analyzed the molecular evolution of the 76 genes that have the strongest genetic association with the disorder. They surveyed human polymorphisms for discrete changes in the human genome that vary between individuals, in order to try and track very recent selective events within specific human populations. They also compared genes between mammalian species to identify selection on primate lineages salient to the evolution of humans and the disorder.

Amongst the genes for which they found positive selection were three genes that have the best functional or reproducible associations with the disorder: disrupted in schizophrenia (DISC1), dystrobrevin-binding protein 1 (DTNBP1) and neuregulin 1 (NRG1).

The selective forces underlying adaptive evolution of these genes remain largely unknown, but these findings are consistent with the hypothesis that schizophrenia is a maladaptive by-product of adaptive changes during human evolution, perhaps associated with creativity and human cognition.

Non-pharmacological and Lifestyle Approaches to Attention-Deficit/Hyperactivity Disorder: 11. Integrated Medicine

The whole point of Integrated Medicine and Integrated Health is to help the person with attention-deficit hyperactivity disorder (ADHD) to become integrated as a person by using an integrated approach to treatment. This kind of comprehensive approach is particularly important for many people with ADHD. I also want to re-emphasize that although ADHD is the approved term for the problem, many people, particularly adults, may have little overt evidence of hyperactivity, and they are better thought of as having “ADD.”

Attentional problems come in all shapes and sizes. Some are so mild that people just need to be shown how to use a day planner and implement some time management scheme. Others need a more aggressive and comprehensive approach. Whatever we do has to be individualized to the person with the problem. Not only do we have to match the plan with the person, we also need to match it with his or her belief system.

It is important to recognize that no one approach is likely to work on its own. Medications may be very helpful, but they are only tools to help people get organized so that they can fulfill their potential. And medications are unlikely to be effective unless we also deal with nutrition, posture, breathing, sleep and environmental stress.

It is also essential to realize that ADHD is highly co-morbid: there is evidence of increased rates of physical problems, including disturbances in thyroid function and cell membrane function throughout the body. The rates of conduct disorder, oppositional defiant disorder, learning disabilities, tics and Tourette’s, worry, anxiety and mood disorders are all much higher in people with ADHD. So high that until recently, many experts believed that ADHD was a symptom rather than a clearly delineated illness. This overlap is also one of the reasons why some people persist in saying that the diagnosis of ADHD is nothing more than a stigmatizing label for socially unacceptable behavior.

Physical

• Medications
• Nutrition
• Posture
• Exercise
• Environment

Over the last few weeks we have spent a lot of time looking at some of the options for treating the physical components of the problem. Now let us look at the rest.

Psychological

• Find out and work with a person’s interests. ADHD is highly dependent on context. A child or adult may have terrible problems with schoolwork, but be able to play a video game for hours on end
• There are multiple intelligences: uncover which are of the greatest importance. It is essential for a person to discover their strengths rather than being forced to focus on the weaknesses. Many people with ADHD find that highlighting text in a book can be useful, while others learn by doing
• People are more likely to follow instructions if they are interesting and emotionally charged
• Bear in mind that many people have poor self-esteem and others suffer from enormous feelings of regret. This is a particular issue for people who may have reached middle age before being diagnosed. We have seen countless people who feel that they have missed out on life. A man working in construction realized that he could have gone to college thirty years ago if only his ADHD had been diagnosed and treated
• Teach visualization skills
• Discover which times of the day are best in terms of attention and alertness
• Learn some simple relaxation techniques
• Learn problem-solving skills

Social

• ADHD can play havoc with relationships. If a child has it, there can be enormous stress on the parents and siblings, all of whom are at higher risk of some features of ADHD themselves. It is essential to help the family with coping skills. ADHD can also put a great deal of stress on a spouse or children. It is also important to know that many people with ADHD have sexual problems that stem from impatience, a low frustration threshold if they cannot have sex when they want it, and real problems with enjoying the moment and taking time to enjoy a romantic interlude. Some people also use sex as a form of self-medication. So it is essential to find out if there are sex or relationship problems and to deal with them, which may need outside help
• Many people with ADHD are socially awkward and may need to learn some social and communication skills
• ADHD and social awkwardness can be magnets for bullies, and it is remarkable how many young people with untreated or inadequately treated ADHD have been bullied. Occasionally they become the perpetrators of bullying to compensate for their difficulties. In either case it is important to discover and deal with bullying. It is one of several reasons why some experts have recommended enrolling a child in martial arts classes. Not only can they help with self-defense, but also the discipline of a martial arts class can work wonders for some people with ADHD
• Role models are important for people with ADHD. It is very helpful, particularly for young people to see that other sufferers have become extremely successful
• It is also important for parents and other family members to develop and maintain a positive image of the person with ADHD
• Develop positive yet realistic career and life goals

Subtle

• Poor breathing techniques can engender many problems. Learning to breath effectively can have profound physical effects as well as stimulating and balancing the subtle systems of the body
• As we have seen, although the research base is very small, yoga, t’ai chi ch’uan or qigong can all be very helpful
• Many people with ADHD are acutely sensitive to “atmosphere:” to the thoughts, feelings and attitudes of other people, and they need specific help to remain grounded and to protect their senses. Some of the flower essences can very helpful for that, as well as some other techniques that we shall be publishing shortly

Spiritual

• How can there be a spiritual component to ADHD? Some people find it difficult to engage in prayer or meditation because of problems with attention. However, with a little perseverance, we have evidence that some forms of meditation may actually help.
• Second the rituals of religion can sometimes provide a wonderful anchor for the person who is having a had time with ADHD.
• Another point is that ADHD is not all bad. Some people who have it become more attuned to nature, animals and to a mystical understanding of the world: an over-reliance on reasoning and linear learning can stifle those perceptions.
• Some people have suggested that ADHD may for the same reasons unlock a rich vein of creativity that might otherwise never have appeared.

There are plenty of books and websites that portray ADHD as a gift. While I have the greatest respect for this approach, it is still important for us not to forget the demonstrable problems caused by inadequately treated ADHD.

ADHD exists, it is treatable, and though it can bring many problems, it can also bring many opportunities. Just so long as we remember to respect every dimension of the person who has it, and remember that if we do not manage it, it will manage us.

Madness and Genius Revisited

I must have heard a thousand times that there’s a fine line between genius and insanity. I have talked before about the possible link between the two through schizotypal personality disorder. It is quite well known that there are two living Nobel Prize winners who have a diagnosis of schizophrenia and many more who have first-degree relatives with it.

There is some very interesting research in the current issue of the Journal of Clinical Investigation from a team of scientists at the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH).

In the latest installment of a story that has been unfolding over the last three decades, they report on their findings concerning a human gene for a master switch in the brain called DARPP-32. Most people inherit a version of a gene that optimizes their brain's thinking circuitry, yet paradoxically also appears to increase risk for schizophrenia, an illness marked by impaired thinking. The main kinds of thinking involve reasoning, abstraction and creativity.

Over the last two decades, studies in animals, most notably by Nobel Laureate Paul Greengard at Rockefeller University, have established that DARPP-32 in the striatum switches streams of information coming from multiple brain chemical systems so that the cortex can process them. Both the neurotransmitter that DARPP-32 works through – dopamine - and the chromosomal site of the DARPP-32 gene have been implicated in schizophrenia.

The NIMH researchers in this new study have identified a common version of the gene and showed how it impacts the way in which two key brain regions exchange information, so affecting a range of functions from general intelligence to attention.

To understand DARPP-32's role in the human brain, they used genetic, structural and functional magnetic resonance imaging and also post-mortem studies to identify the human gene's variants and their functional consequences.

Seventy five percent of subjects had the most common version of the gene, which boosted the activity of circuits in the prefrontal cortex of the brain. This region is the major filter, controller and processor of cognitive information. When active, it increases structural and functional connections and our performance on tasks that involve thinking. It almost certainly does so by increasing gene expression. In 257 affected families, people with schizophrenia were also more likely to have this common version of the DARPP-32 gene.

DARPP-32 appears to shape and control a circuit running between the striatum and prefrontal cortex. The circuit affects key brain functions implicated in schizophrenia, such as motivation, working memory and reward-related learning.

The senior investigator is Daniel Weinberger, who had this to say,

"Our results raise the question of whether a gene variant favored by evolution, that would normally confer advantage, may translate into a disadvantage if the prefrontal cortex is impaired, as in schizophrenia. Normally, enhanced cortex connectivity with the striatum would provide increased flexibility, working memory capacity and executive control. But if other genes and environmental events conspire to render the cortex incapable of handling such information, it could backfire -- resulting in the neural equivalent of a superhighway to a dead-end."

Although several groups of researchers have looked for the possible clinical relevance of DARPP-32, they have had much success. This study shows a strong connection between the molecule and human cognition and also, perhaps, with schizophrenia.

What is also interesting about this finding is that it helps provide us with a mechanism by which environmental stress could lead to cognitive problems.

Apart from the uninformed tirades of Tom Cruise, I see a lot of opinion pieces on websites and YouTube expressing the opinion that psychiatry is baseless, ostensibly because there is no science behind it. By anyone’s standards, this is high level science utilizing a series of state-of-the-art approaches. And another piece of evidence that psychiatry is becoming more science than art, linking the mind, the brain and the environment into one harmonious whole.

Medicine and Creativity

The Lancet medical journal has just published this year's themed issue on the topic of 'Creativity and Medicine'.

If you click on the link, you will be taken to a digital edition of the special issue. The digital edition is an exact facsimile of the print copy and is available for one month. You can turn pages just as you would with a print edition and even print off the pages for your own personal use.

The Lancet is one of the journals that you will find in the "Journal" listing on the left of this blog.

Many of the articles are extremely interesting and thought provoking: "Writing and healing;" "Development of children's creativity to foster peace;" "Healing through art therapy;" "Theatre - a force for health promotion;" "Hospital clowns;" "Healing architecture; " "Healing gardens;" "Chance favors the prepared mind" and "What can the arts bring to medical training?" were some of my favorites, and give you a good flavor of what's in store for you.

You will also see how this fits very precisely with a true Integrated Medicine.

One caution: it IS a medical journal and there are one or two articles near the back that are not for the squeamish.

With that caveat, there is much food for thought in these articles, and the Lancet deserves our thanks for making them available for free. Even if it is only for a month!

Handedness and Immunity

In 1982, one of my mentors, the late Norman Geschwind, and two colleagues – Al Galaburda and Peter Behan - proposed an extraordinary hypothesis. It was that the levels of testosterone to which a baby is exposed before birth influence the development of both the cerebral and immune systems. According to this theory, high levels of testosterone result in greater incidences of left-handedness, deviations from the standard distribution of cerebral functions and increased autoimmune dysfunction. If the theory is right, then male brains should mature later than female brains, and the left hemisphere should mature later than the right.

It is certainly true that if a boy gets a head injury or infection involving the brain, he is less likely to recover than would a girl, and boys are far more likely to have some types of neurodevelopmental problems like dyslexia.

For a while it seemed as if there was also a strong association between left-handedness and certain types of allergy, and also with inflammatory bowel disease. This association with immunity also seemed to be present in mice: those who had left paw preference had more reactive immune systems, and they were thought to be more likely to produce auto-antibodies, suggesting that the central nervous system was involved in the genesis of some autoimmune diseases. Over the years the data has become less clear-cut, but the idea of an association between anomalous cerebral asymmetry and autoimmune disease never completely went away.

Recent data has again found an association between inflammatory bowel disease and laterality. And left-handers really do have more autoimmune disease.

The Geschwind-Galaburda hypothesis proposes that there should be a four-way association among neurodevelopmental disorders, special talents, non-right handedness, and immune disorders. In a huge study of 11,578 children, less than 1% had all four.

So where does this leave us?

The original theory was half right:

1. There is indeed a link between testosterone and early brain development
2. People who are left-handed or have a strong tendency toward left-handedness do seem to be at slightly increased risk of several autoimmune conditions
3. People who are left-handed or have a strong tendency toward left-handedness may have a slightly increased risk of high blood pressure, asthma and migraine
4. People who are left-handed or have mixed handedness are more likely to excel in certain disciplines: creative arts, music, computer programming and mathematics. What we don’t know is whether people with these special skills are more likely to have autoimmune diseases
5. Amongst very successful tennis players,  there are far more left-handers than would be predicted by chance. This supports the idea that support the notion that left-handed people have neurological advantages in performing certain tasks, such as visuospatial visuomotor cognitive tasks.

I was reminded of the way in which Nature seems to like to balance things out a bit: with some notable and famous exceptions, many successful athletes have not done so well academically and many academics would be unlikely to survive on the plains of Africa. Only some of these differences can be explained in terms of early direction and encouragement in school or while growing up: it seems that most of us cannot hope to become the kind of superman that Nietzsche used to dream about.

Perhaps it’s a way of stopping us from getting too full of ourselves.

Child Prodigies

I’ve recently had cause to look at the published literature on child prodigies and there’s not much there. It is very surprising that such an interesting subject has been so little researched.

First a definition from a paper by David Feldman: A “prodigy was a child (typically younger than 10 years old) who is performing at the level of a highly trained adult in a very demanding field of endeavor.” There are three fields in which high-level creative results have been produced before the age of 10: Chess, Mathematics and Music. There are other fields such as art and writing in which young people may be precocious imitators. Pablo Picasso exactly mimicked his father’s drawings. There is an impressive list of child prodigies in other fields as well, but it seems that only in chess, mathematics and music have profound, original insights been contributed by preadolescent children.

There is an interesting association between mathematics and chess: many top chess players are also extremely good at mathematics. In a previous post I mentioned the English Grandmaster John Nunn, and there are many other examples. Men dominate both fields, but that does not necessarily mean that there is a natural gender difference. There’s a very interesting book entitled Breaking Through, by the chess Grandmaster Susan Polgar who was herself a prodigy, as were both of her sisters. Girls have been excluded from many of these events, or they’ve been forced to play only against girls or women. I know a young person who as a pre-teenager wanted to join the school chess club, but only went once, after discovering that all the other members were boys. A shame: she was already quite a strong player.

Both chess and mathematics involve highly developed non-verbal and visuospatial skills. The writer and critic George Steiner had this to say: “The solution of a mathematical problem, the resolution of a musical discord or conclusion of a contrapuntal development, the generation of a winning chess position can be envisaged as spatial regroupings, that have their own internal logic.” He went on to speculate, “All three fields involve enormously powerful but narrowly specialized areas of the cortex. These areas can somehow be triggered into life in a very young child and can develop in isolation form the rest of his psyche. Sexually and socially unformed, very possibly backward in every general respect, the child virtuoso or pre-teenage chess master draws on formidable but wholly localized synapses in the brain.”

In the book The Exceptional Brain, Lee Cranberg and Marty Albert suggested that these “localized synapses” lie in the right hemisphere of the brain, which is primarily involved in non-verbal visuospatial skills and pattern recognition. They also suggested that gender differences in proficiency in chess support the right hemisphere idea. But after reading Susan Polgar’s book, and spending a great deal of time analyzing the world literature on gender differences in cognition, that last point doesn’t convince me.

It is striking that three of the code breakers at Bletchley Park during the second World War, were outstanding international chess players Stuart Milner-Barry, Harry Golombek and Hugh Alexander. These code breakers who helped win the War also utilized similar skills to those needed to master a chess position or to calculate a mathematical problem.

The child prodigies seem to have some things in common:

1. An unusually strong talent in a single area
2. Reasonably high but not necessarily exceptionally high IQ: some people with astronomically high levels of intelligence have had problems with interpersonal adjustment, unless very carefully nurtured as children.
3. Focused energy.
4. Sustained effort to achieve the highest levels in their field: even chess prodigies need thousands of hours of practice, and mathematical prodigies need to work at their field.
5. Unusual self-confidence.

Adults who want to improve in chess are constantly told to practice as much as possible, and to work on pattern recognition and problem solving. It is just the same in music and mathematics.

Although child prodigies may simply have better neurological equipment, usually coupled with extraordinary encouragement by their parents, I am left with a question that I posed in an earlier post. Mozart often said that when he was composing he felt as if he was taking dictation from God. That he was not the one composing, but that he was in effect picking something up from the Universe. I’ve seen countless highly gifted people tell me that their greatest insights in science, music philosophy or chess just “came to them.” The former chess World Champion Tigran Petrosian once said that he could tell when he was out of form when his calculations did not confirm the validity of his first impressions. All this implies unconscious processing to be sure, but I am not sure that it is all in the brain.

Because there is another phenomenon that has also not been much researched, and that is the phenomenon of simultaneous breakthroughs: two or more people in different parts of the world coming up with new creative solutions at the same time and without any personal contact. I shall have more to say about this in another post, but it speaks to the fundamental interconnectedness of all of us.

Maybe the child prodigies not only have special brains and special parents, but they also have access to a store of information not available to everyone.

At least not yet: We already have training methods that help people access accurate information that they did not know consciously. A story for another day.

“Genius is characterized just by the fact that it escapes classification.” --Leopold Infeld (Polish Physicist, 1898-1968)

A Gene for Infidelity?

Last January I wrote about the link between creativity and promiscuity.

I’ve just picked up this month’s copy of the Mensa Magazine, published by British Mensa  and there’s an interesting article by Dr. Desmond Morris entitled “Why brilliant men betray their wives.” Desmond is a national institution in Britain. A zoologist, ethnologist and surrealist painter, he always used to be on television and gained considerable notoriety for his book The Naked Ape that tried to explain human behavior by analogy with apes.

In his latest article Desmond follows some of the same reasoning that I did in my article: many intensely creative people also enjoy risk taking. He just talks about males, but I think that the same principles apply equally to many intensely creative and successful women, who also enjoy taking extreme risks.

Every act of creation demands that we see, feel or think differently about something. Desmond says that every piece of innovation or creativity is an act of rebellion. I only half agree with that: the truly creative person is busily establishing a new level of order. The creative rebel is a stereotype that’s not born out by experimental work on genius and creativity. The creative or innovative act is one of making new connections and in a sense it is also a moment of risk-taking, for the new technique, formula or invention may fail. We recently discussed the way in which resilience is a key to creativity: to keep going in the face of failure or adversity. Even the most highly creative are not every single day: I have known many Nobel Prize winners and award winning artists, and they all have their off days.

Desmond’s article highlights the multiple extra-marital affairs of Albert Einstein, John F. Kennedy, Charlie Chaplin and Bertrand Russell.

He argues that it is the innate compulsion to take risks that leads both to creative brilliance and an inability to remain with just one partner. He pursues the idea that our distant hunting ancestors required a new personality trait: bravery. The successful needed to take risks and be courageous. Desmond then again excludes women from his equation, saying that their reproductive contributions to the tribe made them too important to risk on the hunt. He now fast-forwards to the present, saying that the offspring of the adventurous males could either engage in physical risk-taking or explore new ideas. And that their curiosity leads them to explore not just ideas but novel sexual experiences. Once a “conquest” has been made, the risk-taking adventurer moves on to a new target.

It is certainly true that men are far more likely to die in accidents than are women, but it’s a bit of a stretch to attribute all of that to risk-taking. What about the male difficulties with multi-tasking and to resist peer pressure, to say nothing of much higher rates of substance abuse?

And yes, fame, power and wealth can be powerful aphrodisiacs. But to reduce immoral, dangerous and disrespectful behavior to a risk-taking gene from our distant ancestors seems to me to a wild extrapolation based on a very selective use of a small amount of information.

Because infidelity surely has many more strands to it that just a genetic “itch.” Many highly successful people are enormously narcissistic and so fail to take into account the damage that their infidelity might do to their spouse and children.

Seeing sex as no more than a branch of gymnastics is also off the mark. Even a casual encounter will likely contain emotional, subtle and even spiritual components. If a relationship is failing because those are all missing, it is no surprise if a spouse investigates divorce and other options. But that is not risk taking: it is fulfilling a need that is not being met by the current partner.

Creativity and Resilience

“No great thing is created suddenly, any more than a bunch of grapes or a fig. If you tell me that you desire a fig, I answer you that there must be time. Let it first blossom, then bear fruit, then ripen.”
--Epictetus (Phrygian-born Greek Stoic Philosopher, c.A.D.55- c.A.D.135)

I have written several articles about resilience, and I have begun to talk about some of the methods for developing psychological resilience and also some of the potential consequences of not developing this essential psychological strength.

I’d also like to share with you another aspect of resilience: it is essential ingredient of creativity and of innovation.

I’ve had a longstanding fascination with the creative process, and one of the most robust findings in the research on extraordinary creative achievement is that even the greatest performers in their fields seem to produce the same ratio of undistinguished works to notable ones through their careers. The great chess player wins more often than the average one, but only sometimes produces a truly great creation. Even the best engineers and scientists conduct many unsuccessful experiments. The stories are legion of artists who produce many paintings and works of music that never win recognition and may not even be much good. Many great actors, directors, cricketers and companies have a great many failures behind – and sometimes in front  - of them.

Amongst the many attributes of the high achiever in each of these fields is a remarkable ability to bounce back, to detach from the apparent failure, to see it as an education, and to understand the importance of persistence and perseverance. To take a risk, to take a step back and to learn and adapt if at first it doesn’t succeed. This never means repeating the same strategies over and over again, it means being smart and not being fazed by failure

“Unless you are willing to try, fail miserable, and try again, success won't happen.”
--Phillip Adams (Australian Broadcaster, Filmmaker, Archaeologist and Satirist, 1939-)

I was once working with a company that had just tried to launch a promising new medicine. The initial effort had been a flop and at the time that I became involved, the company had just fired the entire marketing team. Neither the company nor the recently departed team had had the chance to find out what had gone wrong and how to build something new and different. The new team had to start from scratch and, living in constant fear, was burning out at an astonishing rate. The real problem was the inflexibility of the company that was stifling creative solutions to problems. Once that was fixed, things began to improve very quickly.

If anyone ever says that they and the company never accepts failure, it is laudable but impractical.

It’s different if an enterprise fails because people are not pulling their weight; or failing to meet deadlines; or being overly rigid in interpreting rules or just goofing off. But if everyone is trying to help, learning, and being dynamic and flexible, then it’s best not to send them on their way, but instead to see how we can learn from a failure.

And the key for you personally and the key for your company is to learn to develop personal and corporate resilience. Then creative answers have the chance to start flowing.

“Results! Why, man, I have gotten a lot of results. I know several thousand things that won't work.”
--Thomas Alva Edison (American Inventor, 1847-1931)

“No one succeeds without effort.... Those who succeed owe their success to their perseverance.”
--Ramana Maharshi (Indian Hindu Mystic and Spiritual Teacher, 1879-1950)

Critics and Creativity

“Great spirits have always encountered violent opposition from mediocre minds.”
--Albert Einstein (German-born American Physicist and, in 1921, Winner of the Nobel Prize in Physics, 1879-1955)

I have had the incredible privilege of knowing, working with, and sometimes sitting at the feet of more than one hundred of the greatest and most influential thinkers, scientists and spiritual leaders of the last fifty years. I have never been interested in listing them: many wish to retain their privacy, and it is much more important for you to get the message, rather than its origin.

It’s great if a Nobel Laureate or a fourteenth generation teacher transmits his or her insights and wisdom. Yet it remains our responsibility to use all our powers - emotional, intellectual and intuitive - to decide what is right for us. I have seen a T’ai Chi Ch’uan master forget the “form,” a “guru” who neglected the most fundamental part of his own teachings, and a Nobel Laureate misquote a study in which I was involved. Such things happen; it just means that we have to bring our own gifts to bear when we decide how to proceed. Some spiritual teachers deliberately throw in some misinformation to see if we are actually working with their material, and not just sitting passively and soaking it up like a sponge.

After all these years spent with these fine people and scores of complementary practitioners, athletes, musicians, opera singers and ballet dancers, all have told me the same thing: the more creative you are, the more you give the world, the stronger the negative reaction. It almost seems to be a law of nature, to stop anyone form rising too high.

Debate is great! Willful destruction never is. Gently pointing out errors or inconsistencies is one of the marvelous strengths of the Internet. Smashing things and people for fun seems singularly pointless! Think about all the people in the public eye, actors and performers, who have been built up only to be thrown down again.

I’ve always been a gossip magnet: it’s just one of those things that I've come to expect! Yet we recently had something totally bizarre: we received a number of odd messages from people with strange pseudonyms. One made the bizarre claim that I was going to die. Well, I guess that’s a safe prediction for anyone! But with thanks to this modern Cassandra I am not, in fact, even close! I practice what I preach. Experts who have looked at my biophysical and "energetic" profiles think that I’m going to be around for another fifty to seventy years. And I plan to use those years to do what I can for others: helping, guiding, teaching, encouraging and supporting. And as long as people find them helpful, I’m going to keep the blogs, articles, books and CDs coming!

As Mark Twain said:
“The report of my death was an exaggeration.”

And another wise person had this to say:
“Pay no attention to critics. No one ever erected a statue to a critic.”

Odd comments like those recently sent to me are a terrific gift: they help us to see how far we've come with one of the three great pillars of self-realization: detachment. The other two pillars are "Honesty of mind" and "Sincerity of spirit."

You must decide how far along you and I are with those!

Technorati tags: Creativity Criticism Detachment Cassandra

The Passing of the Crazy Diamond

You may have heard of the passing of Syd Barrett, one of the founding members and creative drivers of Pink Floyd. He was only 60 years old.

His extraordinary creativity is well known: his fingerprints were all over the early performances and albums, and he was a muse to a generation of performers. I remember everyone’s consternation as his behavior became progressively more erratic between 1967 and 1968. I was very young then, but we all loved the music.

Some blamed his psychological meltdown on his consumption of prodigious amounts of LSD and all manner of other trendy chemical amusement aids. But in hindsight, he was probably suffering from a psychotic illness, and he was either self-medicating, or the drugs pushed him over the edge. Without doing a full evaluation, I could not say for sure. Although it’s now a moot point, several things make me think that he had a psychotic illness:
1.    His startling type of creativity before and in the early stages of his illness.
2.    There are clues suggesting that he already had problems before become obviously unwell.
3.    The chronicity of his problems are not at all like drug-induced psychosis. I saw a man in Australia who told me that all his years of psychosis were the result of a single “bad trip” in the 1960s. Unlikely.
4.    He suffered for years from diabetes mellitus. Diabetes may be as much as twice as common in people suffering from schizophrenia and bipolar disorder, and also in their first-degree relatives. (England’s first chess grandmaster, Tony Miles, who sadly had a psychotic episode in the late 1980s, also struggled with diabetes for many years, and died at the age of only 46.)

Why does any of this matter now?

If you ever see a young person abusing drugs, be aware that it is not necessarily that he or she is being impulsive or has just fallen in with a bad crowd. It may be that they are self-medicating.

People with major mental illnesses are at increased risk of many other physical illnesses, not all of which are a result of poor lifestyle choices. If you in contact with someone struggling with mental illness, anything that you can do to help them look after their physical health is all to the good.

And finally, a favorite song of mine that was written about Syd. According to legend, by a strange coincidence he arrived at the Abbey Road studio un-announced, at very time that the song was being recorded. It was nice that he was well enough to come and listen.

Remember when you were young, you shone like the sun.
Shine on you crazy diamond.
Now there's a look in your eyes, like black holes in the sky.
Shine on you crazy diamond.
You were caught on the cross fire of childhood and stardom,
blown on the steel breeze.
Come on you target for faraway laughter, come on you stranger,
you legend, you martyr, and shine!

You reached for the secret too soon, you cried for the moon.
Shine on you crazy diamond.
Threatened by shadows at night, and exposed in the light.
Shine on you crazy diamond.
Well you wore out your welcome with random precision,
rode on the steel breeze.
Come on you raver, you seer of visions, come on you painter,
you piper, you prisoner, and shine!

Technorati tags: Syd Barrett Pink Floyd Psychotic illness Diabetes mellitus Substance abuseSelf-medication 

Neurogenesis 101

The great Spanish histologist and Nobel Prize winner in Physiology or Medicine, Santiago Ramón y Cajal, was probably the first modern scientist to say that neurons in the adult brain did not divide.  In other words, humans are born with a finite number of brain cells and an individual cannot develop/grow/replicate new cells over the course of their adult lives. This is an axiom that underlies some parts of the stem-cell debate.

There is emerging research that seems to refute this notion.  I have written a long article for my friends over at Psychiatric Resource Forum discussing the research indicating that humans may have the ability to produce new neurons in key regions of the brain throughout life, a process called neurogenesis.  I also discuss what this means for field of psychiatry.

The concept of neurogenesis also engenders hope for the fields of personal and spiritual development.  I will discuss these at a later date.  I just wanted to link to this article because it provides (along with the links) a good primer on neurogenesis that will be helpful as I write new posts.

Technorati tags: neurogenesis, personal growth, Self Improvement

Unconscious Processing and Intuition

There is a very interesting paper in this week’s Journal Science. It is from a group working at the University of Amsterdam, and their findings are likely to turn one branch of psychology upside down. Let me explain the importance of this work, and how you can start to apply it in your own life.

What the researchers did was to divide their subjects into two groups. In the first experiment the subjects had to decide on a favorite car. One group used a conscious, intellectual reasoning approach and the other group was distracted with puzzles to keep their conscious minds busy before making the decision. When there were only four things to factor into the choice, the intellectuals did better. But when they had to choose on the basis of 12 factors the people using conscious decision-making did much worse than the people who had to make an immediate decision based on unconscious thought processes. In the second experiment shoppers were asked about their satisfaction with items that they had bought. People who bought on the basis of conscious deliberation were much happier with their choices of simple items, while the “unconscious” shoppers preferred their choices of more complex items.

Why is this so important? Since the Enlightenment, science has emphasized the benefits of conscious deliberation in decision-making, and has tended to look down on the whole notion of unconscious thought. Yet this study adds to the growing body of evidence that not only can people think unconsciously, but that for complex decisions, unconscious thought is actually superior. Conscious thought is like a bright torchlight that can only illuminate a few things at a time, and that can lead to some aspects of a problem being given undue attention.

This report supports something that many of us have been teaching for some time. Too much conscious deliberation can actually be counter-productive. Effective thinking needs us to get all the information necessary to make a decision. Then, if we are dealing with a simple decision use conscious thought. But if the decision is complex, it is best left to unconscious thought; in effect to sleep upon it. The answer then tends to appear very suddenly.

There is a secret about the way in which a great deal of progress is made: Most of the major advances in physics have come not from logical progression, but from mystical revelation: Albert Einstein and the theory of relativity, Max Planck and quantum theory, Erwin Schrödinger and wave mechanics, the list is a long one. The great Welsh mathematician and philosopher Bertrand Russell once said of Einstein, that the problem in understanding him was not a difficulty with his logic, but with Einstein’s imagination. He was able to let his mind go to places that others could not, and it came back with answers that nobody else could have conceived of. There is evidence that while most chess players spend virtually all of their time trying to calculate, strong players rely on unconscious processes for most of the game, and only calculate for short periods when their unconscious mind tells them too. There is even evidence from brain imaging studies that average players activate all the cognitive areas of the frontal lobes while playing, with some temporal lobe activity as they try to remember their lessons. By contrast, a chess master uses many regions of his brain at once, and only occasionally activates parts of his frontal lobes when calculation is required.

What this means for us is that we must not be afraid to turn complex problems over to our unconscious minds. I have also spent a great deal of time training people to get used to using their intuition, for this is really one aspect of what we are talking about here. In my book Healing, Meaning and Purpose, I have several sections on developing your intuition.

When you start learning to turn problems over to your unconscious mind, one of the most difficult things is to know when to trust it. So here are some tips:

1. Once you have an answer, now is the time to use your conscious mind to see if the answer that you’ve come up with makes sense.

2. Learn to trust yourself. That may take a little time, but if you have a problem with trusting yourself, you have something tangible to work on.

3. Always be certain that you are prepared to hear whatever answers you receive.

4. Use your intuition to evaluate your intuitions: does the answer “feel” right?

5. Don’t force the process: conscious deliberation follows a linear time scale, unconscious thinking does not; so let insights come in their own time.

6. Always promise yourself that you will take action on any decisions that you make. Your brain and mind will not likely be very cooperative if you ignore the fruits of your unconscious thinking!

“There is no such thing as a logical method of having new ideas…. Every great discovery contains an irrational element of creative intuition.” --Sir Karl Popper (Austrian-born British Philosopher, 1902-1994)

Creativity and Promiscuity

What do Lord Byron, Dylan Thomas and Pablo Picasso have in common? Not only were they all creative, they also had lively and probably exhausting sex lives. British researchers have recently found evidence that this connection may be no coincidence.

Daniel Nettle from the University of Newcastle upon Tyne and Helen Clegg of the Open University have spent some years examining the puzzle of schizophrenia. This is without doubt one of the most savage and distressing illness to afflict humanity. There is a heritable component, yet sufferers themselves often find it very hard to maintain relationships, have many physical illnesses and tend to have fewer children themselves. Yet the illness persists, and indeed appears to have become far more common in the middle of the 18th century, roughly coinciding with the beginning of the Industrial Revolution. The question then is whether some mild forms of the illness may have survival advantage. Theses investigators have been looking at some of the personality traits that may be predictive of schizophrenia. They found high rates of what is known as “Schizotypy” amongst the artists and poets.

The typical features of schizotypal personality disorder are:

1. Unusual experiences, including odd perceptions, magical thinking and sometimes hallucinations

2. Cognitive disorganization

3. Impulsivity

4. Non-conformity with regard to rules and social conventions

5. Often introverted, though some become overly sociable

People with schizotypal personality may develop schizophrenia symptoms if stressed, and they are found more commonly in the families of people with full-blown schizophrenia.

Psychologists have previously found that the creativity of professional artists and poets acts almost like a sexual magnetic, and it has long been thought that creative people are more likely to engage in increased sexual activity, but this research is the first to prove it. The average number of sexual partners for artists and poets was between four and ten, compared with three for non-creative types. Statistics also showed that the average number of sexual partners for both men and women rose in line with an increase in the amount of creative activity.

Links have been made before between bipolar disorder and creativity and also between creativity and schizotypy. An essential feature of creativity is the ability to put together unusual associations and ideas. In the schizotypal person who is creative, this is kept in balance, but in schizophrenia these association can become bizarre. Schizotypy tends to be associated with cognitive activation and sometimes greater sociability.

Apart from art and poetry, it is an open secret in the psychiatric community that several Nobel Prize-winning scientists have schizotypy, at least two have been diagnosed with schizophrenia, including John Nash of Beautiful Mind fame, and several famous Nobel Laureates have first-degree relatives with schizophrenia. The numbers are much higher than in the general population.

Some commentators have suggested that if you want to be lucky in love, perhaps you need to be more creative. We cannot all be a Byron or a Picasso, but I would suggest that injecting a little more creativity into your current relationships and if you are looking for new ones, being more open and creative about how and whom you meet, will likely make encounters more congenial for both of you.

Technorati tags: creativity, schizotypy, Picasso,